Neurological Complications of Renal Disease

Neurological manifestations related to electrolyte disorders, drug toxicity, and uremia are common in chronic kidney disease (CKD). Seizures and coma were frequent complications of acute uremia, whereas peripheral neuropathy and encephalopathy, observed in progressive uremia, were terminal events. Failure to excrete metabolic products causes an accumulation of these products and can lead to severe intoxication. Clinically, the signs and symptoms of uremia can vary widely, depending on the biological characteristics of the patient, the specific type of renal disease, and the time of the uremic intoxication.
Source: Seminars in Pediatric Neurology - Category: Neurology Authors: Source Type: research