Sustained Effects of Neonatal Systemic Lipopolysaccharide on IL-1 β and Nrf2 in Adult Rat Substantia Nigra Are Partly Normalized by a < b > < i > Spirulina < /i > < /b > -Enriched Diet

Conclusion: Early-life infection can negatively affect Nrf2, pAKT, and pGSK-3 β for a long time in SN. A diet enriched with antioxidant and anti-inflammatory phytochemicals can partly restore some, but not all, of the effects on the antioxidant defense, possibly via normalizing effects on pAKT.Neuroimmunomodulation
Source: Neuroimmunomodulation - Category: Allergy & Immunology Source Type: research