The exploration of risk factors of concurrent bacteremia among critically ill patients with severe dengue.

The exploration of risk factors of concurrent bacteremia among critically ill patients with severe dengue. J Med Microbiol. 2016 Nov 07;: Authors: Chen CM, Chan KS, Cheng KC, Chou W, Chao HC, Yeh CY, Yu WL Abstract We investigated the clinical features of intensive care unit (ICU) patients with a concomitant severe dengue infection and bacteremia to identify risk factors for this comorbidity. The records of all ICU dengue patients admitted during a July 31-November 31, 2015 were reviewed. Patients with "concurrent bacteremia" (positive bacterial blood culture within 72 hours of ICU admission) were identified. ICU admission was required for 142 patients; 22 (15.5%) had concurrent bacteremia. Streptococcus spp. was the most common pathogen, then Escherichia coli, and then Staphylococcus spp. Patients with a severe dengue infection and bacteremia had higher APACHE II and TISS scores, C-reactive protein (CRP) levels, leukocyte counts, positive fluid balances, longer activated partial thromboplastin times (APTTs), lactate levels, and more kidney failures, but Controls (severe dengue patients without bacteremia) had higher Glasgow Coma Scale (GCS) scores, higher albumin levels, and more abdominal pain (all p < 0.05). Patients with bacteremia had a higher mortality rate than did Controls (40.9 vs. 18.3%; p = 0.018). Multiple logistic regression analysis showed that bacteremia was significantly positively associated with the following ind...
Source: Journal of Medical Microbiology - Category: Microbiology Authors: Tags: J Med Microbiol Source Type: research