Rate of epilepsy in people with autism and the rate of autism in people with epilepsy are high

Commentary on: Sundelin HE, Larsson H, Lichtenstein P, et al.. Autism and epilepsy: a population-based nationwide cohort study. Neurology 2016;87:192–7. Context Population-based studies can provide information on the risk of people with autism developing epilepsy. Examination of family members of individuals with epilepsy can also provide a likelihood of a genetic link between autism and epilepsy. Sundelin et al carried out a register-based population study aimed at providing HRs for those with autism (ASD, autism spectrum disorder) developing epilepsy, those with epilepsy having ASD and relatives of people with epilepsy developing ASD. Methods Cases were identified using the ICD-9 or ICD-10 codes from the Swedish National Patient Register, which includes nationwide inpatient diagnoses from 1987 and, since 2001, hospital-based outpatient care. Siblings, offspring and parents of all participants with epilepsy were identified, with up to five controls matched for age, sex and county of residence...
Source: Evidence-Based Medicine - Category: Internal Medicine Authors: Tags: EBM Prognosis, Epidemiologic studies, Epilepsy and seizures, Child and adolescent psychiatry Source Type: research