Single-center, single-dose, open-label, randomized, two period crossover study on the bioavailability of methotrexate administered using a novel prefilled, needle-free delivery system, ZENEO.

CONCLUSIONS: This study shows that methotrexate injection via ZENEO is bioequivalent to a conventional needle and syringe in relation to AUC(0-t) and AUC(0-∞). Studies of ZENEO use in patients requiring methotrexate therapy are planned. PMID: 27874307 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research