Global Overexpression of ET-1 Decreases Blood Pressure - A Systematic Review and Meta-Analysis of ET-1 Transgenic Mice

Conclusion:This meta-analysis provides robust evidence that global ET-1 overexpression in mice lowers blood pressure in an age-dependent manner. Older ET-1+/+ mice have a somewhat more pronounced reduction of blood pressure.Kidney Blood Press Res 2016;41:770-780
Source: Kidney and Blood Pressure Research - Category: Urology & Nephrology Source Type: research