Serum Metabolomic Profiles in Neonatal Mice following Oral Brominated Flame Retardant Exposures to Hexabromocyclododecane (HBCD) Alpha, Gamma, and Commercial Mixture

Conclusions: We demonstrate that four days following a single neonatal oral exposure to α-, γ-, and CM-HBCD results in different serum metabolomic profiles, indicating stereoisomer- and mixture-specific effects and possible mechanisms of action. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publication process. Citation: Szabo DT, Pathmasiri W, Sumner S, Birnbaum LS. Serum Metabolomic Profiles in Neonatal Mice following Oral Brominated Flame Retardant Exposures to Hexabromocyclododecane (HBCD) Alpha, Gamma, and Commercial Mixture. Environ Health Perspect; http://dx.doi.org/10.1289/EHP242 Received: 1 October 2015 Revised: 30 December 2015 Accepted: 19 September 2016 Published: 4 November 2016 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our st...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Articles Source Type: research

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Publication date: February 2020Source: Alter, Volume 14, Issue 1Author(s):
Source: ALTER - European Journal of Disability Research - Category: Disability Source Type: research
Abstract Multiple sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central nervous system. The disease affects more women than men and often is diagnosed during a woman's childbearing years. Typical clinical presentations of the disease are extensive and variable, with symptoms that include dysregulated mood, fatigue, vision problems, weakness, tremor, imbalance, abnormal sensations, bladder dysfunction, and heat sensitivity. If a woman aged 15-50 years experiences these neurologic symptoms in isolation or combination, and the symptoms are not explained by other underlying medical conditio...
Source: Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Obstet Gynecol Source Type: research
Authors: Guillaume GM, Vuylsteke ME, Dalcq V, Van der Borght L, Meeus P, de Maeseneer MG Abstract BACKGROUND: To date, it is unclear how treatment of patients with chronic venous disease (CVD) is influenced by national reimbursement systems. In Belgium, catheters or fibers used for endovenous thermal ablation (EVTA) are reimbursed only once in a lifetime. The potential impact of the Belgian public health insurance reimbursement policy on surgical practice in phlebology needs to be investigated. METHODS: Billing data available from the Belgian National Institute for Health and Disability Insurance (NIHDI) were u...
Source: International Angiology - Category: Cardiology Tags: Int Angiol Source Type: research
Authors: Kranz AM, Ross R, Sorbero M, Kofner A, Stein BD, Dick AW Abstract BACKGROUND: Integrating preventive oral health services (POHS) into medical offices may ease access to care for children with intellectual and developmental disabilities (IDD). The authors examined the impact of state policies allowing delivery of POHS in medical offices on receipt of POHS among Medicaid enrollees with IDD. METHODS: The authors used 2006 through 2014 Medicaid data for children with IDD aged 6 months through 5 years from 38 states. IDD were defined using 14 condition codes from Centers for Medicare &Medicaid Services ...
Source: Journal of the American Dental Association - Category: Dentistry Tags: J Am Dent Assoc Source Type: research
CONCLUSION: Given the abrupt and significant life-changing nature of stroke, it is often necessary to manage a diverse array of psychological issues that often cannot be simply managed via psychotropic medications. Moreover, an understanding of the patients' emotional adjustment and issues can help them maximize their rehabilitation, recovery, and community integration. For the cases discussed, psychology consultations were central in helping optimize their rehabilitation and functional outcomes. PMID: 32083601 [PubMed - as supplied by publisher]
Source: NeuroRehabilitation - Category: Rehabilitation Tags: NeuroRehabilitation Source Type: research
Cardiovascular disease was, and still is, our No. 1 killer. It's a major source of our health care costs, and causes disability and related economic loss. At its peak, in the 1960s, among people over age 35, 1 in 100 died of heart disease every year -- a rate more than two-thirds higher than today.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
This study was designed by researchers at X University.Participants: Thirty-seven patients undergoing LSS were randomized to motor imagery group (n=19) and control group (n=18).Main Outcome Measures: Pain was measured by Visual Analogue Scale, disability related to low back pain by Oswestry Disability Index, pain-related fear by Tampa Scale of Kinesiophobia, depression by Beck Depression Inventory, quality of life by World Health Organization Quality of Life Scale-Short Form (WHOQOL-BREF). All assessments were repeated in the preoperative period, three weeks after and six weeks after the surgery.Interventions: Motor imager...
Source: EXPLORE: The Journal of Science and Healing - Category: Complementary Medicine Source Type: research
Conclusions and implicationsSensory Sensitivity Scales (SeSS) can be used to screen sensory sensitivity variability or identify and follow up the outcome of sensory interventions in adults.
Source: Research in Developmental Disabilities - Category: Disability Source Type: research
Daniel Williams challenges the lack of profile and visibility in the media and fashion industry for people living with visual impairment
Source: Disabled World - Category: Disability Tags: Communication Source Type: news
Cupid's Arrow is a dating site created by the disabled for the disabled allowing members to simply and safely seek out others looking for a friend or significant other
Source: Disabled World - Category: Disability Tags: Disabled Dating Source Type: news
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