[Radiotherapy in central neurocytoma and review of literature.]

[Radiotherapy in central neurocytoma and review of literature.]
Cancer Radiother. 2014 Apr 4;
Authors: Canova CH, Riet FG, Idbaih A, Mokhtari K, Mazeron JJ, Feuvret L
Abstract
Central neurocytoma is a rare primary central nervous system tumour of young adults with good prognosis. Typical and atypical forms are described according to various histologic and histopathologic parameters. Central neurocytoma develops in the periventricular areas and is revealed by increased intracranial pressure. The tumour exhibits typical characteristics on CT scan and MRI and a characteristic peak of glycine on spectroscopy-MRI. The main treatment is total resection, which is achievable only in half of the cases. External beam therapy improves local control of partially resected and/or atypical central neurocytoma. Many studies show that stereotactic radiotherapy can be used in the therapeutic management as exclusive treatment, in postoperatives residues and in case of distant recurrence. Chemotherapy is the last line of treatment in refractory forms, especially in the forms with extracranial and/or neuromeningeal spread and in recurrent forms after treatment with surgery and/or radiotherapy.
PMID: 24708940 [PubMed - as supplied by publisher]

Source: Cancer Radiotherapie - April 4, 2014 Category: Cancer & Oncology Authors: Canova CH, Riet FG, Idbaih A, Mokhtari K, Mazeron JJ, Feuvret L Tags: Cancer Radiother Source Type: research