Primary intraoral granulocytic sarcoma: A rare case presenting as generalized gingival enlargement

Thayalan Dineshkumar, Vemuri Suresh, Ramadas Ramya, Krishnan RajkumarJournal of Oral and Maxillofacial Pathology 2016 20(3):523-526Granulocytic sarcoma (GS) is an extremely rare condition involving infiltration of myeloblasts or immature myeloid cells in an extramedullary site. It is also known as chloroma, myeloid sarcoma or extramedullary myeloid tumor. It usually occurs concomitantly with acute myelogenous leukemia or with the onset of blastic phase of chronic myelogenous leukemia. On rare occasions, it evolves even before the onset of leukemias, and when it precedes leukemias without any overt signs, it is referred to as the primary type. Although GSs can involve any body part, localization in the oral cavity is extremely rare. The recognition of this rare primary entity is important because early aggressive chemotherapy can cause regression of the tumor and improve survival. Here, we report a rare case of GS in a nonleukemic 62-year-old female who presented with generalized gingival enlargement involving both maxilla and mandible.

Source: Journal of Oral and Maxillofacial Pathology - September 20, 2016 Category: ENT & OMF Authors: Thayalan Dineshkumar Vemuri Suresh Ramadas Ramya Krishnan Rajkumar Source Type: research