A multicenter retrospective study of mogamulizumab efficacy in adult T-cell leukemia/lymphoma

Mogamulizumab recently became available for the treatment of adult T-cell leukemia/lymphoma (ATL). We conducted a multicenter retrospective study of the efficacy of mogamulizumab in ATL treatment in patients in Japan, and found that mogamulizumab is an effective therapeutic strategy in ATL. There is some concern that the use of mogamulizumab in hematopoietic stem cell transplantation patients might cause severe GVHD. Determining the optimum number of mogamulizumab administrations should be a priority for future studies.

Source: Clinical Lymphoma, Myeloma and Leukemia - September 15, 2016 Category: Hematology Authors: Satoshi Iyama, Tsutomu Sato, Hirofumi Ohnishi, Yuji Kanisawa, Shuichi Ohta, Takeshi Kondo, Akio Mori, Yutaka Tsutsumi, Hiroyuki Kuroda, Yasutaka Kakinoki, Satoshi Yamamoto, Tohru Takahashi, Motohiro Shindo, Yoshihiro Torimoto, Kazuya Sato, Hiroshi Iwasaki Tags: Original Study Source Type: research