A hepatic stellate cell gene expression signature associated with outcomes in hepatitis C cirrhosis and hepatocellular carcinoma after curative resection

Conclusions
This work highlights the unique transcriptional niche of stellate cells, and identifies potential stellate cell targets for tracking, targeting and isolation. Hepatic stellate cell signature expression may identify patients with HCV cirrhosis or postresection HCC with poor prognosis.

Source: Gut - September 7, 2016 Category: Gastroenterology Authors: Zhang, D. Y., Goossens, N., Guo, J., Tsai, M.-C., Chou, H.-I., Altunkaynak, C., Sangiovanni, A., Iavarone, M., Colombo, M., Kobayashi, M., Kumada, H., Villanueva, A., Llovet, J. M., Hoshida, Y., Friedman, S. L. Tags: Hepatic cancer Hepatology Source Type: research