Tamoxifen resistance linked to high estrogen levels in utero

(Georgetown University Medical Center) An animal study suggests that resistance to tamoxifen therapy in some estrogen receptor positive breast cancers may originate from in utero exposure to endocrine disrupting chemicals. The study provides a new path forward in human research as about half of the breast cancers treated with this common cancer therapy do not respond well, say researchers at the Georgetown Lombardi Comprehensive Cancer Center, who led the multi-institutional research.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news