Brugada syndrome: clinical presentation and genotype--correlation with magnetic resonance imaging parameters

Conclusion
Brugada syndrome patients with an SCN5A mutation reveal distinct changes in RV volumes and function when compared with those without an SCN5A mutation. Furthermore, mutation-positive patients have a higher likelihood of a spontaneous type 1 BrS-ECG, which is associated with a higher incidence of clinical events. Cardiovascular magnetic resonance may provide additional insight to distinguish between SCN5A mutation-positive and -negative BrS patients.

Source: Europace - August 30, 2016 Category: Cardiology Authors: Rudic, B., Schimpf, R., Veltmann, C., Doesch, C., Tülümen, E., Schoenberg, S. O., Borggrefe, M., Papavassiliu, T. Tags: Channelopathies Source Type: research