Aspiration Thrombectomy After Intravenous Alteplase Versus Intravenous Alteplase Alone [Clinical Sciences]

Conclusions—
THERAPY did not achieve its primary end point in this underpowered sample. Directions of effect for all prespecified outcomes were both internally and externally consistent toward benefit. It is possible that an alternate method of thrombectomy, primary aspiration, will benefit selected patients harboring large vessel occlusions. Further study on this topic is indicated.

Clinical Trial Registration—
URL: http://www.clinicaltrials.gov. Unique identifier: NCT01429350.

Source: Stroke - August 21, 2016 Category: Neurology Authors: Mocco, J., Zaidat, O. O., von Kummer, R., Yoo, A. J., Gupta, R., Lopes, D., Frei, D., Shownkeen, H., Budzik, R., Ajani, Z. A., Grossman, A., Altschul, D., McDougall, C., Blake, L., Fitzsimmons, B.-F., Yavagal, D., Terry, J., Farkas, J., Lee, S. K., Baxter Tags: Ischemic Stroke Clinical Sciences Source Type: research