ACE Inhibitors in CKD with CHF : Cardiologist proposes … Nephrologist disposes !
I used to tell my students ,the relationship between the heart and kidney is so close , it is never justified for the two departments of Nephrology and Cardiology are physically away by two blocks in our institute .
Kidneys are vital to maintain the volume and pressure of body fluids and heart is responsible for keeping this fluid circulating.
In clinical setting it is a well known secret ,most deaths in patients who are on dialysis is cardiac while most deaths in patients with CHF are renal.
It remains a mystery why kidneys were ever considered as a circulatory organ , when our medical pundits de-compartmentalised human organ systems !
CKD is pre-cardiac failure and CHF is pre-renal failure
The Heart /Kidney affair is so intimate in many pathological situations both either succeed or fail simultaneous or sequentially.
While CKD results in and pressure and volume overload of heart , cardiac failure cause pressure and volume under load (pre-renal factor) which worsen the renal function and aggravate cardiac function alter.
In essence, it is vicious cycle of two serial organs performing the vital circulatory function with body fluids playing a role of diligent mediator.Whenever the kidney fails heart is stretched and stressed to its Frank starling limits by the volume as well as the accompanying HT load.
While text books link these two organ as simple cardio-renal syndrome it is not happening at the level of patient’...
Source: Dr.S.Venkatesan MD - Category: Cardiology Authors: dr s venkatesan Tags: cardiac failure cardiac physiology Cardiology -Therapeutic dilemma cardiology -Therapeutics chf is a ckd equivalent CHF is CKD equivalent Intra renal edema Source Type: blogs
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