Comparison of Points of Departure for Health Risk Assessment Based on High-Throughput Screening Data

Conclusions: The SNCD may serve as a reference level that guides the determination of standardized BMDs for risk assessment based on HTS concentration-response data. The SNCD may also have potential application as a POD for low-dose extrapolation. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publication process. Citation: Sand S, Parham F, Portier CJ, Tice RR, Krewski D. Comparison of Points of Departure for Health Risk Assessment Based on High-Throughput Screening Data. Environ Health Perspect; http://dx.doi.org/10.1289/EHP408 Received: 21 January 2016 Revised: 25 April 2016 Accepted: 13 June 2016 Published: 6 July 2016 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehp508@niehs.nih.gov. Our staff will work with you to assess and meet your a...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Article Source Type: research