The Effect of Nicotine and Tobacco on Aortic Matrix Metalloproteinases in the Production of Aortic Aneurysm.

CONCLUSION: Nicotine and tobacco constituents translate the exposure to cigarette smoke into increased MMP expression through various molecular mechanisms whose interruption can form the basis for pharmacologic management of AAs. PMID: 27363715 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/27363715?dopt=Abstract

Source: Current Vascular Pharmacology - June 23, 2016 Category: Drugs & Pharmacology Authors: Rabkin SW Tags: Curr Vasc Pharmacol Source Type: research