Extended therapeutic window of a novel peptide inhibitor of TRPM2 channels following focal cerebral ischemia.

CONCLUSIONS: These data demonstrate the development of a new peptide inhibitor of TRPM2 channels that provides protection from ischemic stroke in young adult and aged male animals with a clinically relevant therapeutic window.
PMID: 27317297 [PubMed - as supplied by publisher]

Source: Experimental Neurology - June 13, 2016 Category: Neurology Authors: Shimizu T, Dietz RM, Cruz-Torres I, Strnad F, Garske AK, Moreno-Garcia M, Venna VR, Quillinan N, Herson PS Tags: Exp Neurol Source Type: research