DNA Methylation Signature Reveals Cell Ontogeny of Renal Cell Carcinomas.

CONCLUSION: Our data defines the epi-clusters that can discriminate between distinct RCC subtypes and for the first time define the epigenetic basis for proximal versus distal tubule derived kidney tumors.
PMID: 27256309 [PubMed - as supplied by publisher]

Source: Clinical Cancer Research - June 1, 2016 Category: Cancer & Oncology Authors: Malouf GG, Su X, Zhang J, Creighton CJ, Ho TH, Lu Y, Raynal NJ, Karam JA, Tamboli P, Allanick F, Mouawad R, Spano JP, Khayat D, Wood CG, Jelinek J, Tannir NM Tags: Clin Cancer Res Source Type: research