Patterns and trends in the incidence of paediatric and adult germ cell tumours in Australia, 1982–2011

Conclusion Broad similarities in the shape of age-specific incidence curves, particularly for gonadal, central nervous system, and mediastinal tumours provide epidemiological support for commonalities in aetiology among clinically disparate GCT subtypes. Differences in peak ages reflect underlying subtype-specific biological differences. Declining incidence trends for some adult gonadal tumours accords with the global transition in GCT incidence, and supports the possibility of a reduction in prevalence of shared aetiological exposures.
Source: Cancer Epidemiology - Category: Cancer & Oncology Source Type: research