Ambulatory Activity Components Deteriorate Differently across Neurodegenerative Diseases: A Cross-Sectional Sensor-Based Study.

CONCLUSIONS: These findings provide objective evidence that reduced ambulatory activity is a shared feature across different NDDs. Moreover, they reveal that several underlying walking behavior components change with increasing disease duration, yet at a differing rate in different NDDs. This indicates that metric analysis of ambulatory activity might provide ecologically relevant and disease-specific progression and outcome markers in several NDDs.
PMID: 27197840 [PubMed - as supplied by publisher]

Source: Neuro-Degenerative Diseases - May 20, 2016 Category: Neurology Authors: Klenk J, Srulijes K, Schatton C, Schwickert L, Maetzler W, Becker C, Synofzik M Tags: Neurodegener Dis Source Type: research