Current strategies in interventional oncology of colorectal liver metastases.

Current strategies in interventional oncology of colorectal liver metastases. Br J Radiol. 2016 May 10;:20151060 Authors: Gruber-Rouh T, Marko C, Thalhammer A, Nour-Eldin NE, Langenbach M, Beeres M, Naguib NN, Zangos S, Vogl TJ Abstract The adequate treatment of non-resectable liver metastases from colorectal cancer which are resistant to systemic chemotherapy currently provides a great challenge. The aim is to identify and review key strategies in the treatment of colorectal liver metastases. A search for current literature on the topic of interventional strategies for colorectal metastases was performed in Medline in order of achieves this goal. Studies before 2005 and with less than 20 patients treated for colorectal metastases were excluded. Transarterial chemoembolization (TACE), transarterial embolization (TAE) and selective internal radiation therapy (SIRT) were identified as examples of regional strategies for colorectal liver metastases, utilizing the unique blood supply of the liver. Radiofrequency ablation (RFA), microwave ablation (MWA) and cryoablation were selected as examples for currently available ablative techniques. Median survival in the key studies reviewed ranged from 7.7 to 28.6 for TACE, 8.3 to 12.6 for SIRT, 8.2 to 53.2 for RFA and 29 to 43 months for MWA. After review of the literature it can be concluded that interventional oncologic therapies are a safe and effective method for treating colorectal liver me...
Source: The British Journal of Radiology - Category: Radiology Authors: Tags: Br J Radiol Source Type: research