Tumour-educated circulating monocytes are powerful candidate biomarkers for diagnosis and disease follow-up of colorectal cancer

Conclusions
Our study is the first to demonstrate monocyte plasticity in response to tumour-released soluble factors. The identified distinct signature in tumour-educated monocytes might be used as a candidate biomarker in CRC diagnosis and harbours the potential for disease follow-up and therapeutic monitoring.

Source: Gut - May 9, 2016 Category: Gastroenterology Authors: Hamm, A., Prenen, H., Van Delm, W., Di Matteo, M., Wenes, M., Delamarre, E., Schmidt, T., Weitz, J., Sarmiento, R., Dezi, A., Gasparini, G., Rothe, F., Schmitz, R., D'Hoore, A., Iserentant, H., Hendlisz, A., Mazzone, M. Tags: Colon cancer Source Type: research