miR-30-HNF4{gamma} and miR-194-NR2F2 regulatory networks contribute to the upregulation of metaplasia markers in the stomach

Conclusions The interplay of the two transcription factors HNF4 and NR2F2 and their coordinate regulation by miR-30 and miR-194, respectively, represent a miRNA to transcription factor network responsible for the expression of intestinal transcripts in stomach cell lineages during the development of intestinal metaplasia.
Source: Gut - Category: Gastroenterology Authors: Tags: Stomach and duodenum, Pancreatic cancer Source Type: research