miR-30-HNF4{gamma} and miR-194-NR2F2 regulatory networks contribute to the upregulation of metaplasia markers in the stomach
Conclusions
The interplay of the two transcription factors HNF4 and NR2F2 and their coordinate regulation by miR-30 and miR-194, respectively, represent a miRNA to transcription factor network responsible for the expression of intestinal transcripts in stomach cell lineages during the development of intestinal metaplasia.
Source: Gut - Category: Gastroenterology Authors: Sousa, J. F., Nam, K. T., Petersen, C. P., Lee, H.-J., Yang, H.-K., Kim, W. H., Goldenring, J. R. Tags: Stomach and duodenum, Pancreatic cancer Source Type: research
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