Autologous stem cell mobilization in the age of plerixafor

Plerixafor is a potent stem cell mobilizing agent whose cost is prohibitive for routine use. In 277 consecutive patients, the addition of rescue plerixafor during suboptimal G-CSF mobilization or after prior failure of chemotherapy plus G-CSF, was associated with successful mobilization in 97.5% of patients with target collections achieved in 60% of lymphoma and 72% of myeloma patients.
Source: Clinical Lymphoma, Myeloma and Leukemia - Category: Hematology Authors: Tags: Original Study Source Type: research