The impact of neoadjuvant chemotherapy on cardiopulmonary physical fitness in gastro-oesophageal adenocarcinoma.

Conclusions This reduction in AT objectively quantifies a decrease in cardiorespiratory reserve after NAC. Patients with lower cardiorespiratory reserve have increased postoperative morbidity and mortality. Preventing this decrease in cardiorespiratory reserve during chemotherapy, or optimising the timing of surgical resection after recovery of AT, may allow perioperative risk-reduction. PMID: 27138851 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/27138851?dopt=Abstract

Source: Annals of the Royal College of Surgeons of England - May 2, 2016 Category: Surgery Authors: Sinclair R, Navidi M, Griffin SM, Sumpter K Tags: Ann R Coll Surg Engl Source Type: research