23rd Annual “Angels Among Us” 5K Run and Family Fun Walk This Saturday

Contact: Samiha KhannaPhone: 919-695-5334Email: samiha.khanna@duke.eduhttps://www.dukehealth.org  FOR IMMEDIATE RELEASE on Wednesday, April 20, 2016 The Preston Robert Tisch Brain Tumor Center at Duke Health will hold the 23rd Annual “Angels Among Us” 5K run on Saturday, April 23, to benefit brain tumor research.  The race is one of the largest and oldest running events to benefit medical research and is expected to draw more than 3,500 participants this year. Since its beginning in 1994, Angels Among Us has raised more than $18 million for brain tumor research at Duke.  Date: Saturday, April 23, 2016 (rain or shine)  Schedule:  7 a.m. - 5K race registration  8 a.m. - 5K run begins for competitive runners, followed by recreational runners and participants with strollers and wheelchairs 9:30 a.m. - 5K run awards 10:30 a.m. - survivors’ recognition 10:50 a.m. - 3K family walk in Sarah P. Duke Gardens 11:45 a.m. - closing ceremony, team awards and check presentation  Location: Corner of Erwin Road and Flowers Drive, Duke University Medical Center campus  Registration Information.   Benefits: Funds go directly to the Preston Robert Tisch Brain Tumor Center at Duke Health, supporting the acquisition of new equipment, the recruitment of top scientists and the research efforts they pursue.  
Source: DukeHealth.org: Duke Health Features - Category: Pediatrics Tags: Duke Medicine Source Type: news

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Publication date: Available online 10 December 2019Source: Artificial Intelligence in MedicineAuthor(s): Sarah Ali Abdelaziz Ismael, Ammar Mohammed, Hesham HefnyAbstractCancer is the second leading cause of death after cardiovascular diseases. Out of all types of cancer, brain cancer has the lowest survival rate. Brain tumors can have different types depending on their shape, texture, and location. Proper diagnosis of the tumor type enables the doctor to make the correct treatment choice and help save the patient's life. There is a high need in the Artificial Intelligence field for a Computer Assisted Diagnosis (CAD) syste...
Source: Artificial Intelligence in Medicine - Category: Bioinformatics Source Type: research
CONCLUSIONS: Future studies will explore potential mechanisms at the brain-tumor barrier to explain lower cyclophosphamide brain penetration in tumor-bearing mice. These results will be used to further investigate exposure-response relationships in medulloblastoma xenograft models. PMID: 31815662 [PubMed - in process]
Source: J Pharm Pharm Sci - Category: Drugs & Pharmacology Authors: Tags: J Pharm Pharm Sci Source Type: research
Shah Islam Hugh Harvey By HUGH HARVEY, MBBS and SHAH ISLAM, MBBS AI in medical imaging entered the consciousness of radiologists just a few years ago, notably peaking in 2016 when Geoffrey Hinton declared radiologists’ time was up, swiftly followed by the first AI startups booking exhibiting booths at RSNA. Three years on, the sheer number and scale of AI-focussed offerings has gathered significant pace, so much so that this year a decision was made by the RSNA organising committee to move the ever-growing AI showcase to a new space located in the lower level of the North Hall. In some ways it made sense to ...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Artificial Intelligence Health Tech Start-Ups AI Hugh Harvey Radiology RSNA RSNA 2019 RSNA19 Shah Islam Source Type: blogs
AbstractLaser interstitial thermal therapy (LITT) is an emerging modality to treat benign and malignant brain lesions. LITT is a minimally invasive method to ablate tissue using laser‐induced tissue heating and serves as both a diagnostic and therapeutic modality for progressive brain lesions. We completed a single‐center retrospective analysis of all patients with progressive brain lesions treated with LITT since its introduction at our center in August of 2015. Twelve patients have been treated for a total of 13 procedures, of which 10 patients had brain metastases and 2 patients had primary malignant gliomas. Biopsi...
Source: The Oncologist - Category: Cancer & Oncology Authors: Tags: Lung Cancer, Melanoma and Cutaneous Malignancies, Neuro-Oncology, Breast Cancer Brief Communications Source Type: research
Conclusion.We suggest that gliomas with astroblastic features include a variety of molecularly sharply defined entities. Adult ABM harboring molecular features of PXA and HGG should be reclassified. Central nervous system high‐grade neuroepithelial tumors with MN1 alterations and histology of ABM appear to be uncommon in adults. Astroblastic morphology in adults should thus prompt thorough molecular investigation aiming at a clear histomolecular diagnosis and identifying actionable drug targets, especially in the mitogen‐activated protein kinase pathway.Implications for Practice.Astroblastoma (ABM) remains a poorly def...
Source: The Oncologist - Category: Cancer & Oncology Authors: Tags: Neuro-Oncology ‐ Source Type: research
ConclusionsCSF-based metabolomics to a large extent reliably identifies significant metabolic differences between different brain tumors and shows great potential for diagnosis of brain tumors.
Source: Journal of Neurology - Category: Neurology Source Type: research
We present a contemporary analysis of risk of fatal stroke among more than 7.5 million cancer patients and report that stroke risk varies as a function of disease site, age, gender, marital status, and time after diagnosis. The risk of stroke among cancer patients is two times that of the general population and rises with longer follow-up time. The relative risk of fatal stroke, versus the general population, is highest in those with cancers of the brain and gastrointestinal tract. The plurality of strokes occurs in patients older than 40 years of age with cancers of the prostate, breast, and colorectum. Patients of any ag...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
This study is to investigate the mechanism through which DMBT1 exerts its effects on AR progression. METHOD: DMBT1 levels in the nasal lavage (NL) fluid and the nasal mucosa in AR and control groups were determined by ELISA and IHC. Next, mice were sensitized with ovalbumin; intranasal administrations of recombinant DMBT1 were then performed. DMBT1 in the nasal mucosa of mice were determined by IHC and WB. Nasal symptoms were estimated. IL-4 and IL-5 in BAL fluid and eosinophils infiltration in the nasal cavity were measured through ELISA and HE staining, respectively. RESULTS: DMBT1 levels were found to be signi...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - Category: Drugs & Pharmacology Authors: Tags: Biomed Pharmacother Source Type: research
Publication date: Available online 9 December 2019Source: Neurochemistry InternationalAuthor(s): Susan C. Campbell, Carmen Muñoz-Ballester, Lata Chaunsali, William A. Mills, Jennifer H. Yang, Harald Sontheimer, Stefanie RobelAbstractUnprovoked recurrent seizures are a serious comorbidity affecting most patients who suffer from glioma, a primary brain tumor composed of malignant glial cells. Cellular mechanisms contributing to the development of recurrent spontaneous seizures include the release of the excitatory neurotransmitter glutamate from glioma into extracellular space. Under physiological conditions, astrocyt...
Source: Neurochemistry International - Category: Neuroscience Source Type: research
AbstractPineoblastomas (PBs) are rare, aggressive pediatric brain tumors of the pineal gland with modest overall survival despite intensive therapy. We sought to define the clinical and molecular spectra of PB to inform new treatment approaches for this orphan cancer. Tumor, blood, and clinical data from 91 patients with PB or supratentorial primitive neuroectodermal tumor (sPNETs/CNS-PNETs), and 2 pineal parenchymal tumors of intermediate differentiation (PPTIDs) were collected from 29 centres in the Rare Brain Tumor Consortium. We used global DNA methylation profiling to define a core group of PB from 72/93 cases, which ...
Source: Acta Neuropathologica - Category: Neurology Source Type: research
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