Methylation of insulin DNA in response to proinflammatory cytokines during the progression of autoimmune diabetes in NOD mice

Conclusions/interpretation Epigenetic modification of DNA by methylation in response to immunological stressors may be a mechanism that affects insulin gene expression during the progression of type 1 diabetes.

http://link.springer.com/10.1007/s00125-016-3897-4

Source: Diabetologia - April 9, 2016 Category: Endocrinology Source Type: research