Typhoid toxin increases host survival and promotes asymptomatic infection

(PLOS) Genotoxins damage the genetic material in cells and can cause mutations and cancer. Some bacteria code for and produce genotoxins. A study published on April 7th in PLOS Pathogens reports the surprising finding that one of them, typhoid toxin, actually increases survival of the infected host and promotes long-term colonization without causing disease in the host. The work, the authors say 'poses the semantic and biological question of whether 'toxin' is the appropriate designation'.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news