CTGF promotes articular damage by increased proliferation of fibroblast-like synoviocytes in rheumatoid arthritis.

CONCLUSIONS: Our findings indicate that CTGF plays a crucial role in the proliferation of FLS in RA and probably contributes to synovial lining cell hyperplasia and eventually to joint destruction in patients with RA. PMID: 27044368 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/27044368?dopt=Abstract

Source: Scandinavian Journal of Rheumatology - April 3, 2016 Category: Rheumatology Authors: Ding S, Duan H, Fang F, Shen H, Xiao W Tags: Scand J Rheumatol Source Type: research