SSRI‐antipsychotic combination in psychotic depression: sertraline pharmacokinetics in the presence of olanzapine, a brief report from the STOP‐PD study

ConclusionSertraline pharmacokinetics were similar to historical descriptions in populations not taking antipsychotics. Unlike our unexpected finding that sertraline increases olanzapine apparent clearance, olanzapine exposure had no impact on sertraline pharmacokinetics. Copyright © 2016 John Wiley & Sons, Ltd.

Source: Human Psychopharmacology: Clinical and Experimental - February 29, 2016 Category: Psychiatry Authors: Simon J. C. Davies, Benoit H. Mulsant, Alastair J. Flint, Barnett S. Meyers, Anthony J. Rothschild, Ellen M. Whyte, Margaret M. Kirshner, Denise Sorisio, Bruce G. Pollock, Robert R. Bies, Tags: Short Communication Source Type: research