Glutathione S-transferase in the midgut tissue of gypsy moth (Lymantria dispar) caterpillars exposed to dietary cadmium

Publication date: Available online 6 April 2016 Source:Environmental Toxicology and Pharmacology Author(s): Milena Vlahović, Larisa Ilijin, Marija Mrdaković, Dajana Todorović, Dragana Matić, Jelica Lazarević, Vesna Perić Mataruga Activity of glutathione S-transferase (GST) in midgut of gypsy moth caterpillars exposed to 10 and 30μg Cd/g dry food was examined. Based on the enzyme reaction through conjugation with glutathione, overall activity remained unaltered after acute and chronic treatment. No-observed-effect-concentration (10μg Cd/g dry food) significantly increased activity only after 3-day recovery following cadmium administration. Almost all comparisons of the indices of phenotypic plasticity revealed statistically significant differences. Despite the facts that GST has important role in xenobiotic biotransformation, our results indicate that this enzyme in insect midgut does not represent the key factor in cadmium detoxification.
Source: Environmental Toxicology and Pharmacology - Category: Environmental Health Source Type: research