Time-Varying Effects of Prasugrel Versus Clopidogrel on the Long-Term Risks of Stroke After Acute Coronary Syndromes: Results From the TRILOGY ACS Trial [Brief Reports]

Conclusions— We observed a potential late treatment effect for prasugrel versus clopidogrel for a reduced risk of ischemic stroke in medically managed patients with ACS aged <75 years. These hypothesis-generating findings suggest that longer duration and more potent platelet inhibition with prasugrel may be associated with lower risk of ischemic stroke after 12 months. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00699998.
Source: Stroke - Category: Neurology Authors: Tags: Cerebrovascular Disease/Stroke, Acute Coronary Syndromes Brief Reports Source Type: research