The Dualistic Model of Ovarian Carcinogenesis
Since our proposal of a dualistic model of epithelial ovarian carcinogenesis more than a decade ago, a large number of molecular and histopathologic studies were published that have provided important insights into the origin and molecular pathogenesis of this disease. This has required that the original model be revised and expanded to incorporate these findings. The new model divides type I tumors into three groups: i) endometriosis-related tumors that include endometrioid, clear cell, and seromucinous carcinomas; ii) low-grade serous carcinomas; and iii) mucinous carcinomas and malignant Brenner tumors.
Source: American Journal of Pathology - Category: Pathology Authors: Robert J. Kurman, Ie-Ming Shih Tags: Review Source Type: research
More News: Brenner Tumor | Cancer & Oncology | Carcinoma | Endometrial Cancer | Endometriosis | Epithelial Cancer | Mucinous Carcinoma | Mucinous Ovarian Cancer | Ovarian Cancer | Ovaries | Pathology | Serous Carcinoma | Study