Abstract P1-01-08: An impending avalanche-breast cancer among women >= 90 years of age

This study redefines age extreme in breast pathology to better correlate with current patient demographics, and provides characteristics of breast cancer in this population. Little information exists about the breast cancer in extremely old women. This investigation elucidates the growing number of breast cancer diagnoses in extremely old women (≥90 years) in a single institution in 2000s.MATERIALS AND METHODS: The database of Yale University Department of Pathology was searched for the terms: "breast carcinoma," "age ≥90" for the past 15 years. Clinicopathologic features of the cases that fit the criteria were studied.RESULTS: A total of 135 patients (134 female; 1 male) aged ≥90 years were identified with a diagnosis of infiltrating carcinoma. A surge in breast cancer diagnoses among elderly patients was noted in 2000s compared to the earlier decade. Only 10 cases were diagnosed between 1990 and 1999 (one case/year) compared to 125 cases diagnosed between 2000 and 2015 (8.3 cases/year). Of these 135 patients, 117 had infiltrating ductal carcinoma (IDC); 16 had infiltrating lobular carcinoma (ILC),1 had pure squamous cell carcinoma. One patient had IDC and ILC ipsilaterally, while another had bilateral IDC. The median age was 92 (range: 90-107), median tumor size was 2.0 cm (range: 0.2-13.0), and the median modified Bloom San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2016;76(4 Suppl):Abstract nr P1-01-08.
Source: Cancer Research - Category: Cancer & Oncology Authors: Tags: Poster Session Abstracts Source Type: research