Overdose deaths from common sedatives have surged, new study finds

Headlines about America’s worsening drug epidemic have focused on deaths from opioids—heroin and prescription painkillers such as OxyContin. But overdose deaths have also soared among the millions of Americans using benzodiazepine drugs, a class of sedatives that includes Xanax, Valium, and Klonopin, according to a study.
Source: ScienceDaily Headlines - Category: Science Source Type: news

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The objectives of this article are to describe the reorganization of the three levels of psychiatric care for inmates in France in the context of Covid-19 pandemic and to have a look at the impact of lockdown measures and early releases on mental health of prisoners. METHODS: This work is based on a survey conducted in April 2020 in France among psychiatric healthcare providers working in 42 ambulatory units for inmates and in the 9 full-time inpatient psychiatric wards exclusively for inmates called "UHSAs" (which stands for "unités hospitalières spécialement aménagées...
Source: L Encephale - Category: Psychiatry Tags: Encephale Source Type: research
ConclusionsWe reveal a novel role for the stress hormone cortisol in modulating the transport of opioids across the BBB, which could contribute to their abuse or overdose. Our updated BBB model represents a powerful tool available to researchers, clinicians, and drug manufacturers for understanding the mechanisms by which opioids access the CNS.
Source: Fluids and Barriers of the CNS - Category: Neuroscience Source Type: research
BACKGROUND: The United States (US) and Canada are in the midst of an opioid overdose epidemic. Many people who use illicit drugs (PWUD) do not call an emergency number 911 at the scene of an overdose due to fear of arrest. In the US and Canada, when an ind...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
AbstractPurpose of ReviewWith the growing need for donor hearts and longer transplant waiting lists, there is a growing interest in expanding the donor pool by reconsidering previously excluded donor candidates. There has been an increase in solid organ availability due to drug overdose deaths in the setting of the recent opioid epidemic. However, these donors often have transmissible infections such as hepatitis C. In this review, we discuss the challenges associated with heart transplantation from hepatitis C –infected donors as well as the recent advancements that are making the use of these organs possible.Recent...
Source: Current Heart Failure Reports - Category: Cardiology Source Type: research
(Bentham Science Publishers) In the past two decades more than 700,000 people have died from a drug overdose in the United States. In 2017, more than 68% of the drug overdose deaths involved an opioid. To help stem this epidemic, Highmark Inc. developed, implemented and evaluated a series of quality management-focused opioid interventions utilizing a three-pronged public health approach.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
This article is republished from The Conversation under a Creative Commons license. Read the original article. The post Why More Must be Done to Fight Bogus COVID-19 Cure Claims appeared first on Inter Press Service.
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Global Headlines Health Source Type: news
BACKGROUND: The spread of illicitly manufactured fentanyl has the potential to greatly increase the fatal overdoses in many places in the world. The purpose of this paper is to analyse the evolution of fentanyl use epidemic in Estonia. METHODS: this scop...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
When it comes to health concerns, the COVID-19 pandemic is top of mind for most people right now. And that’s for good reason. But there is some very good non-COVID health news that may not be getting the attention it deserves. According to the CDC, the rates of six of the top 10 causes of death in this country, which account for about three-quarters of all deaths, have been declining. That’s remarkable. And these improvements are occurring despite an aging population and an obesity epidemic that affects several health conditions. Six positive health trends Let’s look at the trends in these conditions...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Cancer Health Health trends Heart Health Source Type: blogs
AbstractOpioids are widely misused and account for almost half of overdose deaths in the United States. The cost in terms of lives, health care, and lost productivity is significant and has been declared a national crisis. Fentanyl is a highly potent mu opioid receptor (MOR) agonist and plays a significant role in the current opioid epidemic; Fentanyl and its analogs (fentalogs) are increasingly becoming one of the biggest dangers in the opioid crisis. The presence of fentalogs in the illicit market is thought to play a significant role in the recent increase in opioid ÔÇÉrelated deaths. Although there is both rodent homol...
Source: Drug Testing and Analysis - Category: Drugs & Pharmacology Authors: Tags: SHORT COMMUNICATION Source Type: research
Abstract Identifying persons with hepatitis C virus (HCV) infection has become an urgent public health challenge because of increasing HCV-related morbidity and mortality, low rates of awareness among infected persons, and the advent of curative therapies (1). Since 2012, CDC has recommended testing of all persons born during 1945-1965 (baby boomers) for identification of chronic HCV infection (1); urban emergency departments (EDs) are well positioned venues for detecting HCV infection among these persons. The United States has witnessed an unprecedented opioid overdose epidemic since 2013 that derives primarily f...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
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