Intestine-specific homeobox (ISX) induces intestinal metaplasia and cell proliferation to contribute to gastric carcinogenesis

Conclusions ISX expression induced by H. pylori infection may lead to IM and hyperproliferation of gastric mucosa through CDX1/2 and cyclinD1 expression, contributing to gastric carcinogenesis.

http://link.springer.com/10.1007/s00535-016-1176-2

Source: Journal of Gastroenterology - February 12, 2016 Category: Gastroenterology Source Type: research