Type-1 interferons contribute to oxygen glucose deprivation induced neuro-inflammation in BE(2)M17 human neuroblastoma cells

Conclusions: This study confirms a role for type-1 IFN signalling in the neuro-inflammatory response following OGD in vitro and suggests its modulation through therapeutic blockade of IFNAR1 may be beneficial in reducing hypoxia-induced neuro-inflammation.

http://www.jneuroinflammation.com/content/11/1/43

Source: Journal of Neuroinflammation - March 6, 2014 Category: Neurology Authors: Myles MinterMoses ZhangRobert AtesJuliet TaylorPeter Crack Source Type: research