Novel Oral Anticoagulation During Pulmonary Vein Isolation and Cardioversion.

Novel Oral Anticoagulation During Pulmonary Vein Isolation and Cardioversion. Cardiovasc Hematol Disord Drug Targets. 2015;15(2):110-4 Authors: Fastner C, Behnes M, Ansari U, Akin I Abstract Atrial fibrillation is an age-dependent disease with symptomatic and prognostic implications. Treatment options include rhythm as well as rate control. However, there is a need for anticoagulation depending on calculated individual annual risk. Treatment options include antiplatelet therapy, oral anticoagulation and the use of novel oral anticoagulation (NOACs). To date, the safety and efficacy of NOACs in atrial fibrillation is established in large mega-trials. However, there is still concern on the use of NOACs in invasive procedures such as coronary angiography, electrophysiological procedures, and general surgical procedures. This review will give an overview about current data of NAOCs in procedures for rhythm control (pulmonary vein isolation and current cardioversion). PMID: 26666328 [PubMed - in process]
Source: Cardiovascular and Hematological Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Cardiovasc Hematol Disord Drug Targets Source Type: research

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Publication date: Available online 10 December 2019Source: Journal of Clinical NeuroscienceAuthor(s): Junya Aoki, Kentaro Suzuki, Satoshi Suda, Seiji Okubo, Masahiro Mishina, Kazumi KimuraAbstractBackgroundSince acute fluid-attenuated inversion recovery vascular hyperintensity (FVH) is indicative of disordered blood flow, FVH is considered a marker of acute major arterial occlusion. Conversely, the role of the absence of FVH (negative-FVH) remains unknown.MethodsConsecutive stroke patients were studied via magnetic resonance angiography, within 24 h of onset and major arterial occlusion. All patients were examined usi...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
ConclusionConventional RFA using PV potential based mapping and ablation with 8 mm tip catheters is safe for patients with PAF. Theintermediate term outcome is satisfactory and cost effective in our setting with limited resources.
Source: Indian Heart Journal - Category: Cardiology Source Type: research
In Reply We agree with Popkirov that left atrial volume is a better marker of incident atrial fibrillation than atrial diameter; however, we did not have these data available at all of the sites participating in the New Approach Rivaroxaban Inhibition of Factor Xa in a Global Trial Versus ASA to Prevent Embolism in Embolic Stroke of Undetermined Source (NAVIGATE-ESUS) trial. Recently completed and ongoing studies will help determine if our observation has a clinical role and may provide additional data on left atrial size and function. Once all of these data are available, guidelines committees will likely make recommendat...
Source: JAMA Neurology - Category: Neurology Source Type: research
Written by Meyers, edits by SmithA 50-ish year old man was working construction when he suddenly collapsed. Coworkers started CPR within 1 minute of collapse. EMS arrived within 10 minutes and continued CPR and ACLS, noting alternating asystole and sinus bradycardia during rhythm checks. He received various ACLS medications and arrived at the ED with a perfusing rhythm.Initial vitals included heart rate around 100 bpm and BP 174/96. Here is his initial ECG, very soon after ROSC:What do you think?Sinus tachycardia.  There is incomplete RBBB (QRS duration less than 120 ms).  There is diffuse STD, maximal in V4-V5 a...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
Yasada et  al (N Engl J Med 2019;381:1103, PMID 31475793) conducted a prospective randomized multicenter trial of 2236 patients with atrial fibrillation (AF) who had undergone percutaneous coronary intervention or coronary artery bypass grafting more than 1 year earlier or who had angiographically confirmed coronary artery disease not requiring revascularization. Patients were randomized to monotherapy with rivaroxaban or combination therapy with rivaroxaban plus a single antiplatelet agent. The primary efficacy end point was a composite of stroke, systemic embolism, myocardial infarction, unstable ang ina requiring r...
Source: Heart Rhythm - Category: Cardiology Authors: Tags: EP News Source Type: research
A 66-year-old male was diagnosed as having an incidental large right sinus of Valsalva aneurysm (SVA) on transthoracic echocardiography when he presented with paroxysmal atrial fibrillation. He had a normally functioning trileaflet aortic valve. Computed tomography angiography revealed a right SVA that measured 26  × 25 × 32 mm and a second left SVA that measured 8 mm in maximum diameter (Figure 1A, B).
Source: Heart, Lung and Circulation - Category: Cardiology Authors: Tags: Image Source Type: research
ConclusionPatients admitted to AMU with suspected TIAs had relevant imaging and tests completed as per guidelines. 89 % had US Carotid Dopplers which were on average done 33h from admission. 58% of patients had inpatient heart monitoring. The average length of stay was 3 days but three patients stayed in AMU for up to 5 days. Protected imaging slots for AMU would expedite investigations and reduce inpatient stay.
Source: Age and Ageing - Category: Geriatrics Source Type: research
Publication date: Available online 27 August 2019Source: Journal of Cardiology CasesAuthor(s): Koichi Furui, Itsuro Morishima, Yasunori Kanzaki, Hideyuki TsuboiAbstractCoronary vasospasm is an emerging potentially lethal complication of catheter ablation for atrial fibrillation (AF), however, its mechanism in this setting has not been well elucidated.A 55-year-old man with symptomatic paroxysmal AF underwent pulmonary vein isolation under sedation with propofol. The procedure was completed without any complications. Fifteen months later, a repeated session was performed because of AF recurrence. Initially, a high-dose infu...
Source: Journal of Cardiology Cases - Category: Cardiology Source Type: research
Publication date: Available online 23 August 2019Source: Journal of Cardiology CasesAuthor(s): Shohei Moriyama, Taku Yokoyama, Kei Irie, Mamoru Ito, Kenji Tsuchihashi, Mitsuhiro Fukata, Hitoshi Kusaba, Toru Maruyama, Koichi AkashiAbstractFluorouracil (5-FU), a commonly used anticancer agent, has potent cardiotoxicity that is mediated by vascular endothelial injury and vasospasm. Here, we report a patient demonstrating atrial fibrillation (AF), which was most likely induced by vasospasm mediated by 5-FU.A 69-year-old man presented with dysphagia and was diagnosed with advanced esophageal cancer. Frequent paroxysms of atrial...
Source: Journal of Cardiology Cases - Category: Cardiology Source Type: research
Coronary CT angiography (CCTA) is an accurate non-invasive tool for the evaluation of coronary artery bypass graft (CABG). However, inability to sustain a long breath-hold, high heart rate (HR) and atrial fibrillation may affect image quality. Moreover, radiation exposure is still a matter of some concern. A scanner combining 0.23-mm spatial resolution, new iterative reconstruction and fast gantry rotation time has been recently introduced in the clinical field. The aims of our study were to evaluate interpretability, radiation exposure and diagnostic accuracy of CCTA performed with the latest generation of cardiac-CT scan...
Source: Journal of Cardiovascular Computed Tomography - Category: Radiology Authors: Tags: Research paper Source Type: research
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