The Vascular Endothelium in Chronic Kidney Disease: A Novel Target for Aerobic Exercise

Endothelial dysfunction occurs in chronic kidney disease (CKD) and increases the risk for cardiovascular disease. The mechanisms of endothelial dysfunction seem to evolve throughout kidney disease progression, culminating in reduced L-arginine transport and impaired nitric oxide bioavailability in advanced disease. This review examines the hypothesis that aerobic exercise may reverse endothelial dysfunction by improving endothelial cell L-arginine uptake in CKD.
Source: Exercise and Sport Sciences Reviews - Category: Sports Medicine Tags: Articles Source Type: research