NeuroSigma touts preliminary eTNS traumatic brain injury trial results

NeuroSigma Systems today released preliminary data from a trial of its Monarch trigeminal nerve stimulation system designed to treat combat veterans with traumatic brain injuries, citing improvements in memory, anxiety and brain activity. The results were presented at the North American Neuromodulation Society’s meeting in Las Vegas, the company said. The trial was performed at the Veterans Affairs West Los Angeles Medical Center, and results showed improvements in symptoms of TBI and desired changes in brain activity, according to the company. “We are pleased by the preliminary results reported by Dr. Langevin and his colleagues. Neuroimaging data indicate that 8 weeks of nightly eTNS treatment can produce a lasting desired influence on the activity of specific brain areas that are linked to TBI, along with improvements in memory, anxiety, and other symptoms that are common in patients with TBI. TBI not only affects many of our combat veterans, but may also result from motor vehicle accidents and sports-related injuries, as highlighted by recent attention to chronic traumatic encephalopathy, or CTE, among players from the National Football League.  We look forward to continued positive results and completion of this Phase I trial,” chief medical officer Dr. Ian Cook said in a press release. The Monarch eTNS system is composed of a small pulse-generator and single-use electric patch applied to the forehead, with signals transmitted through lea...
Source: Mass Device - Category: Medical Equipment Authors: Tags: Neuromodulation/Neurostimulation Clinical Trials NeuroSigma Source Type: news

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Conclusions: Bipolar disorder is common among primary care patients presenting with depression; it is often treated exclusively in primary care. Clinicians should be alert for symptoms of bipolar disorder in undiagnosed patients, know what symptoms probabilistically suggest bipolar versus unipolar depression, have expertise in providing ongoing treatment to diagnosed patients, and be knowledgeable about managing common medication-related side effects and comorbidities. Prompt and accurate diagnosis is critical. PMID: 31311335 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
DiscussionAs psychotherapy is among the treatments of choice for most adult psychiatric disorders, a systematic review evaluating the benefits and harms of short-term compared with long-term psychotherapy is urgently needed. It is the hope that this review will be able to inform best practice in treatment and clinical research of these highly prevalent and burdensome disorders.Systematic review registrationPROSPEROCRD42019128535
Source: Systematic Reviews - Category: International Medicine & Public Health Source Type: research
Purpose of review To review the literature and provide a guide to assessing patients with problematic interactive media use (PIMU). Recent findings 0.3–1.0% of the world population meets criteria for internet gaming disorder (IGD). 26.8–83.3% of adolescents meeting criteria for internet addiction have comorbid attention-deficit/hyperactivity disorder. IGD is associated with increased anxiety and social anxiety/phobias. Group counseling, cognitive behavioral therapy, and sports intervention are associated with significant reductions in internet addiction. Summary With the Diagnostic and Statistical Manua...
Source: Current Opinion in Pediatrics - Category: Pediatrics Tags: ADOLESCENT MEDICINE: Edited by Sara F. Forman and Sarah Pitts Source Type: research
Authors: Marcus S, Malas N, Dopp R, Quigley J, Kramer AC, Tengelitsch E, Patel PD Abstract This column describes the establishment of the Michigan Child Care Collaborative (MC3), a statewide telepsychiatry consultation program that provides support to primary care providers (PCPs) in meeting the mental health needs of youths and perinatal women. The MC3 program provides cost-effective, timely, remote consultation to primary care providers in an effort to address the lack of access and scarcity of resources in child, adolescent, and perinatal psychiatry. Data from 10,445 service requests are summarized. Common diagn...
Source: Psychiatric Services - Category: Psychiatry Tags: Psychiatr Serv Source Type: research
When Grace Friedman was diagnosed with ADHD at 12 years old, she didn’t know much about it. What she did know was that it was hard to make friends, her emotions seemed to be “on steroids,” and focusing on homework and in class felt impossible. It also was difficult to accept that her brain and body worked differently than the average student’s. It was frustrating that she had to work harder on every assignment, staying up later and later just to finish a few math problems. Friedman was convinced that because of these differences, she wouldn’t be able to succeed. She feared she’d “n...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: ADHD and ADD Books Children and Teens College Disorders General Habits Motivation and Inspiration Self-Esteem Self-Help Stress Students Success & Achievement attention Attention Deficit Hyperactivity Disorder Self Care self Source Type: blogs
The present study examined the associations between cyberbullying involvement and sociodemographic characteristics, autistic social impairment and attention-deficit/hyperactivity disorder and oppositional defiant disorder (ODD) symptoms in 219 adolescents ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Publication date: Available online 2 July 2019Source: Pharmacological ResearchAuthor(s): Maria Rosaria Domenici, Antonella Ferrante, Alberto Martire, Valentina Chiodi, Rita Pepponi, Maria Teresa Tebano, Patrizia PopoliAbstractAdenosine A2A receptor (A2AR) is a G-protein coupled receptor that regulates several important functions in the central nervous system. Large amount of preclinical data suggests that the A2AR could represent a target for the development of new therapeutic strategies for different neuropsychiatric conditions. In this review we will recapitulate and discuss the most relevant studies on the role of A2ARs...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
Authors: Ilario C, Alt A, Bader M, Sentissi O Abstract ADHD is the most common psychiatric disorder of childhood. It is considered to be a neurodevelopmental disorder that may persist from chilhood into adulthood. In childood it is associated with several outcomes such as inattention, hyperactivity and impulsivity. Symptoms may change as a person gets older with an increased risk of developing psychiatric comorbidities such as depression, anxiety and substance addiction. However, recent studies diverge from the traditional perspective. These authors hypothesized that ADHD may appear in adulthood, not as a continuat...
Source: L Encephale - Category: Psychiatry Tags: Encephale Source Type: research
Abstract The present study examined the associations between cyberbullying involvement and sociodemographic characteristics, autistic social impairment and attention-deficit/hyperactivity disorder and oppositional defiant disorder (ODD) symptoms in 219 adolescents with high-functioning autism spectrum disorder (ASD). Moreover, the associations between cyberbullying involvement and depression, anxiety, and suicidality were also examined. Adolescents self-reported higher rates of being a victim or perpetrator of cyberbullying than were reported by their parents. Increased age and had more severe ODD symptoms were si...
Source: Journal of Autism and Developmental Disorders - Category: Psychiatry Authors: Tags: J Autism Dev Disord Source Type: research
Authors: Geoffroy PA, Micoulaud Franchi JA, Lopez R, Schroder CM, membres du consensus Mélatonine SFRMS Abstract Melatonin is a hormone secreted by the pineal gland at night. This hormone has many physiological functions, the main one being to synchronise individuals' biological rhythms. Exogenous melatonin has the same chronobiotic action, even at small doses (0.125mg). In addition, a sleep-inducing (soporific) action appears to occur in a dose-effect relationship, i.e. as the dose increases. In psychiatric disorders, these two effects could have interesting applications in clinical practice. The French ins...
Source: L Encephale - Category: Psychiatry Tags: Encephale Source Type: research
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