Serum-derived bovine immunoglobulin/protein isolate in the alleviation of chemotherapy-induced mucositis

Conclusions Twice daily oral gavage of SBI was well-tolerated and reduced the incidence, severity and duration of irinotecan-induced mucositis. SBI was associated with less pronounced changes in inflammatory cell levels and tissue damage to colon and jejunum. Ongoing experiments aim to investigate the mechanisms of SBI-associated gastrointestinal protection.
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research