Perioral dermatitis: still a therapeutic challenge.

PERIORAL DERMATITIS: STILL A THERAPEUTIC CHALLENGE. Acta Clin Croat. 2015 Jun;54(2):179-85 Authors: Mokos ZB, Kummer A, Mosler EL, Čeović R, Basta-Juzbašić A Abstract Perioral dermatitis is a common and often chronic dermatosis. In its classic form, it primarily affects women aged 15 to 45 years, but there are also variants including lupus-like and granulomatous perioral dermatitis, where granulomatous form is more common in childhood and affects mostly prepubescent boys. The etiopathogenesis of the disease remains unclear, but there is a frequent finding of prolonged use of topical products, especially corticosteroids, in the treatment of rosacea and seborrheic dermatitis, preceding the clinical manifestation of perioral dermatitis. Other causes important for the occurrence of the disease include various skin irritants, as well as other physical and hormonal factors, which all share the epidermal barrier dysfunction as an underlying main pathogenic factor. Clinical presentation of papulovesicular eruption in the perioral region with a typical narrow spared zone around the edge of the lips is characteristic. Therapeutic approach should be individually addressed, depending on the severity of clinical presentation and patient's age, with special attention to patient's education and continuous psychological support. In mild forms of perioral dermatitis, 'zero therapy' is the treatment of choice. In the initial treatment period, pati...
Source: Acta Clinica Croatica - Category: Journals (General) Tags: Acta Clin Croat Source Type: research