Coagulation and Fibrinolytic Activity of Tenecteplase and Alteplase in Acute Ischemic Stroke [Brief Reports]

Conclusions— In patients with acute ischemic stroke, alteplase 0.9 mg/kg caused significant disruption of the fibrinolytic system, whereas tenecteplase 0.25 mg/kg did not, consistent with the trend toward lower intracerebral hemorrhage incidence with tenecteplase in the ATTEST study. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01472926.
Source: Stroke - Category: Neurology Authors: Tags: Treatment, Ischemic Stroke, Thrombosis Brief Reports Source Type: research