BLT1 antagonist LSN2792613 reduces infarct size in a mouse model of myocardial ischaemia-reperfusion injury

Conclusion
Selective BLT1 inhibition with LSN2792613 reduces inflammation and apoptosis following IR, resulting in reduced IS, and therefore might be a promising strategy to prevent myocardial IR injury.

Source: Cardiovascular Research - November 17, 2015 Category: Cardiology Authors: de Hoog, V. C., Bovens, S. M., de Jager, S. C. A., van Middelaar, B. J., van Duijvenvoorde, A., Doevendans, P. A., Pasterkamp, G., de Kleijn, D. P. V., Timmers, L. Tags: Cardiac biology and remodelling Source Type: research