Funtabulously Frivolous Friday Five 125

Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia…introducing Funtabulously Frivolous Friday Five 125 Question 1 How often does acute angioedema occur as a complication of IV thrombolysis for acute stroke? In which patients is it most common? Which part of the body is typically affected? + Reveal the Funtabulous Answer expand(document.getElementById('ddet415804920'));expand(document.getElementById('ddetlink415804920')) Angioedema occurs in 1.3% – 5% of cases. Patients taking ACE-inhibitors are predisposed. It often involves the orolingual region ipsilateral to the side of hemiparesis [Reference] Question 2 What syndrome is characterized by a rash, fever, lymphadenopathy, characteristic haematologic abnormalities such as eosinophilia, thrombocytopenia, atypical lymphocytosis and visceral organ involvement presenting within 8 weeks of initiation of, typically, anti-convulsant therapy? What 2 anti-convulsants are usually the cause? + Reveal the Funtabulous Answer expand(document.getElementById('ddet1339821387'));expand(document.getElementById('ddetlink1339821387')) Drug rash with eosinophilia and systemic symptoms (DRESS syndrome) It affects approximately 1 per 1500 new users of phenytoin and carbamazepine [Reference] The mortality rate associated with DRESS syndrome is approximately 10%, the majority due to fulminant liver failure [Reference] Question 3 Â...
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Frivolous Friday Five angioedema Bryant's sign Chvostek sign DRESS syndrome Kindling Stabler's sign Source Type: blogs