Magnolol inhibits growth of gallbladder cancer cells through the p53 pathway

In conclusion, our study is the first to report that magnolol has an inhibitory effect on the growth of GBC cells and that this compound may have potential as a novel therapeutic agent for the treatment of GBC.

This study investigated the effects of magnolol on the growth of GBC cells. The results indicated that magnolol inhibited GBC cell growth in vitro and in vivo via the p53 pathway. This work provided a rationale for Magnolol as a novel therapeutic agent for GBC.

Source: Cancer Science - October 26, 2015 Category: Cancer & Oncology Authors: Maolan Li, Fei Zhang, Xu'an Wang, Xiangsong Wu, Bingtai Zhang, Ning Zhang, Wenguang Wu, Zheng Wang, Hao Weng, Shibo Liu, Guofeng Gao, Jiasheng Mu, Yijun Shu, Runfa Bao, Yang Cao, Jianhua Lu, Jun Gu, Jian Zhu, Yingbin Liu Tags: Original Article Source Type: research