Targeting Proline Biosynthesis in Melanoma

This study demonstrates that melanoma cells are sensitive to disruption of proline synthesis and provides a proof-of-concept that the proline synthesis pathway can be therapeutically targeted in melanoma tumors for tumor inhibitory efficacy. Mol Cancer Res; 13(10); 1408–20. ©2015 AACR.

Source: Molecular Cancer Research - October 18, 2015 Category: Cancer & Oncology Authors: Kardos, G. R., Wastyk, H. C., Robertson, G. P. Tags: Oncogenes and Tumor Suppressors Source Type: research