Suppression of murine autoimmune myocarditis achieved with direct renin inhibition.

CONCLUSION: Our results suggest that aliskiren ameliorates EAM by suppressing T-cell activation and inflammatory cytokines, and has potential as a treatment for myocarditis.
PMID: 26475067 [PubMed - as supplied by publisher]

Source: Journal of Cardiology - October 13, 2015 Category: Cardiology Authors: Takamura C, Suzuki JI, Ogawa M, Watanabe R, Tada Y, Maejima Y, Akazawa H, Komuro I, Isobe M Tags: J Cardiol Source Type: research