Oral Vitamin D Supplements Increase Serum 25-Hydroxyvitamin D in Postmenopausal Women and Reduce Bone Calcium Flux Measured by 41Ca Skeletal Labeling [Nutrition and Disease]

Conclusion: In healthy postmenopausal women, increasing serum 25(OH)D primarily affects calcium transfer from the central compartment to a fast exchanging compartment; it is possible that this represents transfer from the extracellular space to the surface of bone. A serum 25(OH)D concentration of ~40 μg/L achieves ~90% of the expected maximal effect on this transfer rate. This trial was registered at clinicaltrials.gov as NCT01053481.

Source: Journal of Nutrition - October 1, 2015 Category: Nutrition Authors: Schild, A., Herter-Aeberli, I., Fattinger, K., Anderegg, S., Schulze-Konig, T., Vockenhuber, C., Synal, H.-A., Bischoff-Ferrari, H., Weber, P., von Eckardstein, A., Zimmermann, M. B. Tags: Nutrition and Disease Source Type: research